Neurotensin type 2 receptor is involved in fear memory in mice

  title={Neurotensin type 2 receptor is involved in fear memory in mice},
  author={R. Yamauchi and E. Wada and Sari Kamichi and D. Yamada and H. Maeno and M. Delawary and T. Nakazawa and T. Yamamoto and K. Wada},
  journal={Journal of Neurochemistry},
  • R. Yamauchi, E. Wada, +6 authors K. Wada
  • Published 2007
  • Biology, Medicine
  • Journal of Neurochemistry
  • Neurotensin receptor subtype 2 (Ntsr2) is a levocabastine‐sensitive neurotensin receptor expressed diffusely throughout the mouse brain. Previously, we found that Ntsr2‐deficient mice have an abnormality in the processing of thermal nociception. In this study, to examine the involvement of Ntsr2 in mouse behavior, we performed a fear‐conditioning test in Ntsr2‐deficient mice. In the contextual fear‐conditioning test, the freezing response was significantly reduced in Ntsr2‐deficient mice… CONTINUE READING
    30 Citations
    Increased ethanol consumption and preference in mice lacking neurotensin receptor type 2.
    • 21
    Quantified Coexpression Analysis of Central Amygdala Subpopulations
    • 37
    • PDF


    Specific involvement of neurotensin type 1 receptor in the neurotensin‐mediated in vivo dopamine efflux using knock‐out mice
    • 26
    Immunohistochemical distribution of NTS2 neurotensin receptors in the rat central nervous system
    • 102
    The effects of deleting the mouse neurotensin receptor NTR1 on central and peripheral responses to neurotensin.
    • 107
    • PDF
    Regional and cellular distribution of low affinity neurotensin receptor mRNA in adult and developing mouse brain
    • 63
    Pharmacological, molecular and functional characterization of glial neurotensin receptors
    • 47
    Neurotensin enhances glutamate excitotoxicity in mesencephalic neurons in primary culture
    • 20
    Tissue distribution and cellular localization of the levocabastine-sensitive neurotensin receptor mRNA in adult rat brain.
    • 68