Neurotensin receptor expression in prostate cancer cell line and growth effect of NT at physiological concentrations
@article{Seethalakshmi1997NeurotensinRE, title={Neurotensin receptor expression in prostate cancer cell line and growth effect of NT at physiological concentrations}, author={L. Seethalakshmi and S. P. Mitra and P. Dobner and M. Menon and R. Carraway}, journal={The Prostate}, year={1997}, volume={31} }
Neurotensin (NT), a neuroendocrine peptide, exerts trophic effects in vivo and stimulates growth of some tumor cells in vitro. Androgen‐sensitive prostate cells derived from lymph node carcinoma of the prostate (LNCaP) secrete NT and exhibit growth responses to NT. This study examines NT secretion, NT receptor and NT‐growth responses in androgen‐independent prostatic carcinoma (PC3) cells derived from prostate adenocarcinoma metastatic to bone.
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