Neurostimulatory and ablative treatment options in major depressive disorder: a systematic review

  title={Neurostimulatory and ablative treatment options in major depressive disorder: a systematic review},
  author={Pablo Andrade and Lieke H. M. Noblesse and Yasin Temel and Linda Ackermans and Lee Wei Lim and Harry W. M. Steinbusch and Veerle Visser-Vandewalle},
  journal={Acta Neurochirurgica},
  pages={565 - 577}
IntroductionMajor depressive disorder is one of the most disabling and common diagnoses amongst psychiatric disorders, with a current worldwide prevalence of 5–10% of the general population and up to 20–25% for the lifetime period.Historical perspectiveNowadays, conventional treatment includes psychotherapy and pharmacotherapy; however, more than 60% of the treated patients respond unsatisfactorily, and almost one fifth becomes refractory to these therapies at long-term follow-up… 

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    Current topics in behavioral neurosciences
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Vagus nerve stimulation for epilepsy and depression

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