Neurospora tryptophan synthase. Characterization of the pyridoxal phosphate binding site.

Abstract

Tryptophan synthase, which catalyzes the final step of tryptophan biosynthesis, is a multifunctional protein that requires pyridoxal phosphate for two of its three distinct enzyme activities. Tryptophan synthase from Neurospora crassa, a homodimer of two 75-kDa subunits, was shown to bind 1 mol of pyridoxal phosphate/mol of subunit with a calculated… (More)

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Cite this paper

@article{Pratt1988NeurosporaTS, title={Neurospora tryptophan synthase. Characterization of the pyridoxal phosphate binding site.}, author={Michelle L. Pratt and J A Demoss}, journal={The Journal of biological chemistry}, year={1988}, volume={263 14}, pages={6872-6} }