Neuroserpin, a thrombolytic serine protease inhibitor (serpin), blocks transplant vasculopathy with associated modification of T-helper cell subsets.

@article{MunuswamyRamanujam2010NeuroserpinAT,
  title={Neuroserpin, a thrombolytic serine protease inhibitor (serpin), blocks transplant vasculopathy with associated modification of T-helper cell subsets.},
  author={Ganesh Munuswamy-Ramanujam and Erbin Dai and Liying Liu and Mira Shnabel and Yun ming Sun and Mee Yong Bartee and David A. Lomas and Alexandra R Lucas},
  journal={Thrombosis and haemostasis},
  year={2010},
  volume={103 3},
  pages={545-55}
}
Thrombolytic serine proteases not only initiate fibrinolysis, but also are up-regulated in vascular disease and acute inflammatory responses. Although the serine protease inhibitor (serpin) plasminogen activator inhibitor-1 (PAI-1) is considered a main regulator of thrombolysis, PAI-1 is also associated with vascular inflammation. The role of other serpins… CONTINUE READING