Neuroscience. Stout guards of the central nervous system.

@article{Mechoulam2003NeuroscienceSG,
  title={Neuroscience. Stout guards of the central nervous system.},
  author={Raphael Mechoulam and Aron H. Lichtman},
  journal={Science},
  year={2003},
  volume={302 5642},
  pages={
          65-7
        }
}
Endocannabinoids have paradoxical effects on the mammalian nervous system: Sometimes they block neuronal excitability and other times they augment it. In their Perspective, Mechoulam and Lichtman discuss new work (Marsicano et al.) showing that activation of the cannabinoid receptor CB1 by the endocannabinoid anandamide protects against excitotoxic damage in a mouse model of kainic acid-induced epilepsy. 

Citations

Publications citing this paper.
SHOWING 1-10 OF 16 CITATIONS

Similar Papers

Loading similar papers…