Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes

@article{Castellanos2002NeuroscienceOA,
  title={Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes},
  author={F. Castellanos and R. Tannock},
  journal={Nature Reviews Neuroscience},
  year={2002},
  volume={3},
  pages={617-628}
}
  • F. Castellanos, R. Tannock
  • Published 2002
  • Psychology, Medicine
  • Nature Reviews Neuroscience
  • Research on attention-deficit/hyperactivity disorder (ADHD), a highly prevalent and controversial condition, has, for the most part, been descriptive and atheoretical. The imperative to discover the genetic and environmental risk factors for ADHD is motivating the search for quantifiable intermediate constructs, termed endophenotypes. In this selective review, we conclude that such endophenotypes should be solidly grounded in the neurosciences. We propose that three such endophenotypes — a… CONTINUE READING
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