Neuroscience of apathy and anhedonia: a transdiagnostic approach

@article{Husain2018NeuroscienceOA,
  title={Neuroscience of apathy and anhedonia: a transdiagnostic approach},
  author={M. Husain and J. Roiser},
  journal={Nature Reviews Neuroscience},
  year={2018},
  volume={19},
  pages={470-484}
}
Apathy and anhedonia are common syndromes of motivation that are associated with a wide range of brain disorders and have no established therapies. Research using animal models suggests that a useful framework for understanding motivated behaviour lies in effort-based decision making for reward. The neurobiological mechanisms underpinning such decisions have now begun to be determined in individuals with apathy or anhedonia, providing an important foundation for developing new treatments. The… Expand
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