Neuropsychological manifestations in children with Sydenham’s chorea after adjunct intravenous immunoglobulin and standard treatment

  title={Neuropsychological manifestations in children with Sydenham’s chorea after adjunct intravenous immunoglobulin and standard treatment},
  author={Claire Gregorowski and C. Lochner and Lindi Imelda Martin and Candice Simmons and Martin Kidd and Kathleen G Walker and Jo M. Wilmshurst and Soraya Seedat},
  journal={Metabolic Brain Disease},
This was an exploratory study comparing neuropsychological manifestations of Sydenham’s chorea (SC), 6 months after initiation of treatment, in children who had received intravenous immunoglobulins as an adjunct to standard treatment, with those who had received standard treatment. We included a non-SC control group for comparison. We hypothesized that compared to controls, children with SC who had received prior intravenous immunoglobulins would demonstrate less pronounced impairments compared… 
Treatment of Sydenham’s Chorea: A Review of the Current Evidence
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Treatment of Sydenham's Chorea with Intravenous Immunoglobulin, Plasma Exchange, or Prednisone
Clinical improvements appeared to be more rapid and robust in the intravenous immunoglobulin and plasma exchange groups than in the prednisone group, and larger studies are required to confirm these clinical observations and to determine if these treatments are cost-effective for this disorder.
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It is suggested that intravenous methyl‐prednisolone followed by oral prednisone is an effective and well‐tolerated treatment of refractory SC.
Distinguishing PANDAS from Sydenham's chorea: case report and review of the literature.
Treatment of Sydenham Chorea With Intravenous Immunoglobulin
A randomized study made of the outcomes of 10 children treated with standard management alone compared to 10 who received additional intravenous immunoglobulin, and all three outcome measurement tools found improved outcomes in the group that received intravenous immune globulin.
Beneficial use of immunoglobulins in the treatment of Sydenham chorea
It is indicated that treatment with intravenous immunoglobulins (IVIG) is effective in patients with Sydenham chorea (SC), a rare but impressive clinical manifestation following streptococcal infection.
Sydenham's chorea is associated with decreased verbal fluency.
An update on the treatment of Sydenham’s chorea: the evidence for established and evolving interventions
Small studies have demonstrated trends to support the use of immunoglobulins and steroids as therapeutic interventions for children affected by Sydenham’s chorea.
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