Neuropsychological and neuroimaging markers in early versus late-onset Alzheimer's disease.

@article{Kaiser2012NeuropsychologicalAN,
  title={Neuropsychological and neuroimaging markers in early versus late-onset Alzheimer's disease.},
  author={Natalie C Kaiser and Rebecca J. Melrose and Collin Y. Liu and David L. Sultzer and Elvira Jim{\'e}nez and Michael M. Su and Lorena Monserratt and Mario F. Mendez},
  journal={American journal of Alzheimer's disease and other dementias},
  year={2012},
  volume={27 7},
  pages={520-9}
}
BACKGROUND Early-onset Alzheimer's disease (EOAD) has been overshadowed by the more common late-onset AD (LOAD). Yet, the literature indicates EOAD may have less hippocampal-memory presentations and more focal neocortical localization early in the disease. OBJECTIVE To evaluate these proposed differences between these 2 forms of AD and to explore what they inform about differences in AD pathophysiology. METHODS In all, 21 patients with EOAD and 24 patients with LOAD matched for disease… CONTINUE READING
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