Neuropsychological Consequences of Opiate Use
@article{Gruber2007NeuropsychologicalCO, title={Neuropsychological Consequences of Opiate Use}, author={Staci A. Gruber and Marisa M. Silveri and Deborah A. Yurgelun-Todd}, journal={Neuropsychology Review}, year={2007}, volume={17}, pages={299-315} }
Approximately 3.7 million individuals have used heroin and other opiate substances in their lifetime. Despite increasing knowledge of the effects of heroin, it remains the most abused opiate and use among adults has recently increased. The empirical literature examining the neurocognitive effects of acute and chronic opioid use remains limited; however, findings to date suggest that the use of opiates has both acute and long-term effects on cognitive performance. Neuropsychological data…
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References
SHOWING 1-10 OF 117 REFERENCES
Neuropsychological functioning in methadone maintenance patients versus abstinent heroin abusers.
- PsychologyDrug and alcohol dependence
- 2005
Neuropsychological functioning in opiate addicts.
- PsychologyThe Journal of nervous and mental disease
- 1982
Performance on neuropsychological tests was shown to be independent of current or past levels of opiate use and to be of little prognostic significance in relation to treatment outcome, but a comparatively strong association was noted between measures of neuroPsychological functioning and educational achievement.
Methadone maintenance improves cognitive performance after two months of treatment.
- PsychologyExperimental and clinical psychopharmacology
- 2006
Results suggest that opiate-dependent subjects exhibit significant improvement in cognitive function after MM treatment, and no effect of illicit drug use was observed when the sample was stratified by urine toxicology results.
Neuropsychological performance in opiate addicts after rapid detoxification.
- Psychology, MedicineDrug and alcohol dependence
- 1987
Intellectual and neuropsychological functions in young men with heavy and long-term patterns of drug abuse.
- Psychology, MedicineThe American journal of psychiatry
- 1975
Intellectual and neuropsychological tests sensitive to brain dysfunction revealed no intergroup differences, and this finding casts some doubt on other reports suggesting that long-term drug abuse results in neuro psychological disorders.
Cerebral metabolism in opiate-dependent subjects: effects of methadone maintenance.
- Psychology, MedicineThe Mount Sinai journal of medicine, New York
- 2000
The results of this study suggest that neurobiological abnormalities can persist in the brain of a chronic opiate user several years after detoxification from methadone.
Profile of Executive and Memory Function Associated with Amphetamine and Opiate Dependence
- Psychology, BiologyNeuropsychopharmacology
- 2006
While performance of female drug users was normal, male drug users showed significant impairment compared to both their female counterparts and male controls, and there was no difference in performance between current and former drug users.
Profiles of Cognitive Dysfunction in Chronic Amphetamine and Heroin Abusers
- Psychology, BiologyNeuropsychopharmacology
- 2000
Cognitive impairment among methadone maintenance patients.
- Psychology, MedicineAddiction
- 2000
In addition to high rates of psychiatric morbidity, MMPs also show cognitive deficits compared to matched controls, and a history of alcohol dependence and repeated exposure to overdose increase the likelihood of cognitive impairment.