Neuropsychological, neuroanatomical, and neurophysiological consequences of CNS chemotherapy for acute lymphoblastic leukemia.

@article{Moleski2000NeuropsychologicalNA,
  title={Neuropsychological, neuroanatomical, and neurophysiological consequences of CNS chemotherapy for acute lymphoblastic leukemia.},
  author={M Moleski},
  journal={Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists},
  year={2000},
  volume={15 7},
  pages={603-30}
}
  • M Moleski
  • Published 2000 in
    Archives of clinical neuropsychology : the…
Medical treatment for acute lymphoblastic leukemia (ALL) has improved survival rates to 70% for children currently diagnosed with this disease. Intrathecal (IT) chemotherapy replaced CNS radiation therapy (CRT) for those with a favorable diagnosis as research revealed cognitive deficits associated with CRT. The literature pertaining to the potential adverse intellectual and neurophysiological consequences of IT chemotherapy is reviewed. It is concluded that IT chemotherapy may not be a benign… CONTINUE READING
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