Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain.

@article{Onaivi2006NeuropsychobiologicalEF,
  title={Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain.},
  author={Emmanuel S. Onaivi},
  journal={Neuropsychobiology},
  year={2006},
  volume={54 4},
  pages={231-46}
}
For over a decade, until recently, it was thought that marijuana acts by activating brain-type cannabinoid receptors called CB1, and that a second type called CB2 cannabinoid receptor was found only in peripheral tissues. Neuronal CB2 receptors in the brain had been controversial. We reported the discovery and functional presence of CB2 cannabinoid receptors in the mammalian brain that may be involved in depression and drug abuse and this was supported by reports of identification of neuronal… CONTINUE READING
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