Neuropsychiatric symptoms in dementia.

@article{Radue2019NeuropsychiatricSI,
  title={Neuropsychiatric symptoms in dementia.},
  author={Rebecca M. Radue and Art Walaszek and Sanjay Asthana},
  journal={Handbook of clinical neurology},
  year={2019},
  volume={167},
  pages={
          437-454
        }
}
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12 Citations
Background Citations
2

12 Citations

Neuropsychiatric Symptoms of Alzheimer's Disease in Down Syndrome and Its Impact on Caregiver Distress.
TLDR
NPS are frequent and severe in individuals with Down syndrome and AD, contributing to caregiver distress, and NPS in DS must be considered of critical relevance demanding management and treatment.
Is Hyperthyroidism a Possible Etiology of Early Onset Dementia?
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It is essential to detect and manage hyperthyroidism at an earlier stage since hyperthy thyroidroidism increases the risk of dementia, and the possibility of using antithyroid treatment in euthyroid dementia is yet to be studied extensively.
Mood Disorders
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The medications frequently used with newly identified mood disorders and the common side effects of these medications are highlighted.
The agitated older adult in the emergency department: a narrative review of common causes and management strategies
TLDR
The common causes and non‐pharmacologic and pharmacologic management of agitation in older adults, with a specific focus on dementia, delirium, and pain are discussed.
Dementia in diabetes mellitus and atherosclerosis: Two interrelated systemic diseases
Importance of Distinguishing Reactive and Proactive Aggression in Dementia Care
  • L. Volicer
  • Psychology
    Journal of geriatric psychiatry and neurology
  • 2020
TLDR
Reactive aggression should not be labeled “aggressors” because this behavior could be caused by unmet persons’ needs, pain and poor communication with care providers, and antidepressant treatment can be helpful.
Enhanced Association of Tau Pathology and Cognitive Impairment in Mild Cognitive Impairment Subjects with Behavior Symptoms.
TLDR
Enhanced associations between tauopathy and cognitive impairment are present in MCI subjects with behavior symptoms, which is more prominent in the presence of elevated amyloid pathology.
Humanism in the Age of COVID-19: Renewing Focus on Communication and Compassion
TLDR
Placing emphasis on using these techniques to maximize humanism in the care of COVID-19 patients during this crisis has the potential to bring improvements to ED patient care well after this pandemic has passed.
Tailored Activity Program (TAP-BR): Proposition of an outpatient care version and evaluation of its impacts on dementia - A pilot study
TLDR
The outpatient version of TAP-BR can be easily applied, has a positive impact on reducing the BPSD in older people, and improves the emotional state of caregivers, with emphasis on the variable depression.
Programa Personalizado de Atividades (TAP-BR): proposição de uma versão ambulatorial e avaliação dos seus impactos na demência - Estudo piloto
Resumo Introdução O Programa Personalizado de Atividades (TAP-BR) é um programa de intervenção em terapia ocupacional que apresenta resultados promissores na redução dos sintomas comportamentais e…
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References

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Management of Neuropsychiatric Symptoms of Dementia in Clinical Settings: Recommendations from a Multidisciplinary Expert Panel
TLDR
An approach is constructed describing the sequential and iterative steps of managing NPS in real‐world clinical settings that can be used as a basis for integrating nonpharmacological and pharmacological approaches and could be implemented in research and clinical care.
Assessment and management of behavioral and psychological symptoms of dementia
TLDR
The paradigm shift needed to fully institute tailored treatments for people and families dealing with these symptoms in the community is discussed and non-pharmacologic approaches with the strongest evidence base involve family care giver interventions are discussed.
The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia.
TLDR
The APA's most recent practice guideline on antipsychotic treatment in patients with dementia appears to have done just that, with a thorough, balanced, accurate, and current review of available treatments based on medical and scientific literature.
Clinicopathological correlates of behavioral and psychological symptoms of dementia
TLDR
A review of the neuroimaging and neuropathology literature indicates that BPSD are the expression of regional rather than diffuse brain pathology, and that strictly neuropathological explanations are likely to be insufficient to explain B PSD.
Nonpharmacologic management of behavioral symptoms in dementia.
TLDR
Common behavioral symptoms in dementia are characterized and a strategy for selecting evidence-based nonpharmacologic dementia treatments is described, which can significantly improve quality of life and patient-caregiver satisfaction.
Olanzapine as a possible treatment of behavioral symptoms in vascular dementia: risks of cerebrovascular events
TLDR
It is suggested that olanzapine could be a safe and effective treatment even for elderly population in suitable doses and receiving the adequate follow–up, as shown in patients eligible for this open–label study.
Dementia Caregiver Burden: a Research Update and Critical Analysis
TLDR
An updated review of the determinants of caregiver burden and depression, with a focus on care demands and especially the differential effects of various neuropsychiatric symptoms or symptom clusters, finds the disturbing nature of disruptive behaviors cuts across dementia conditions.
Frontotemporal dementia: latest evidence and clinical implications
TLDR
FTD is an underdiagnosed group of neurological syndromes comprising multiple variants with distinct neurobiological profiles and presentations and there is an array of potential novel therapeutic targets, although data concerning their effectiveness are still preliminary or preclinical.
Longitudinal course of behavioural and psychological symptoms of dementia: systematic review
TLDR
There were clinically relevant differences in the longitudinal courses of different BPSD, and apathy was the only symptom with high baseline prevalence, persistence and incidence during the course of dementia.
Sequential drug treatment algorithm for agitation and aggression in Alzheimer’s and mixed dementia
TLDR
This algorithm-based approach for drug treatment of agitation/aggression in Alzheimer’s/mixed dementia has been implemented in several Canadian Hospital Inpatient Units and impact should be assessed in future research.
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