Neuropsychiatric lupus: clinical and imaging aspects.

  title={Neuropsychiatric lupus: clinical and imaging aspects.},
  author={Robin L. Brey},
  journal={Bulletin of the NYU hospital for joint diseases},
  volume={65 3},
  • Robin L. Brey
  • Published 2007 in Bulletin of the NYU hospital for joint diseases
Neuropsychiatric lupus (NPSLE) manifestations are common in adults and children and are associated with an increase in both morbidity and mortality. Cognitive dysfunction, when standardly assessed using sensitive neurocognitive instruments, is the most common NPSLE manifestation. The pathogenic etiologies of NPSLE manifestations are likely to be multifactorial and may involve autoantibody production, microangiopathy, intrathecal production of proinflammatory cytokines and athersclerosis. It is… CONTINUE READING
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