Neuroprotective strategies targeting apoptotic and necrotic cell death for stroke

@article{Yuan2008NeuroprotectiveST,
  title={Neuroprotective strategies targeting apoptotic and necrotic cell death for stroke},
  author={Junying Yuan},
  journal={Apoptosis},
  year={2008},
  volume={14},
  pages={469-477}
}
It has been a major challenge to develop effective therapeutics for stroke, a leading cause of death and serious debilitation. Intensive research in the past 15 years have implicated many regulators and the related mechanisms by which neuronal cell death is regulated. It is now clear that even a brief ischemic stroke may trigger complex cellular events that lead to both apoptotic and necrotic neuronal cell death in a progressive manner. Although efforts at developing specific chemical… CONTINUE READING

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