Neuroprotective role of estrogens: relationship with insulin/IGF-1 signaling.

@article{Alonso2012NeuroprotectiveRO,
  title={Neuroprotective role of estrogens: relationship with insulin/IGF-1 signaling.},
  author={Ana Alonso and Celestino Gonz{\'a}lez Gonz{\'a}lez},
  journal={Frontiers in bioscience},
  year={2012},
  volume={4},
  pages={
          607-19
        }
}
Postmenopausal women have an elevated risk of developing a neurodegenerative disease. These clinical observation supported by basic research, suggest that estrogens are neuroprotective. Insulin resistance represents an independent factor in the etiology of age-associated disease and metabolic syndrome should be considered as a contributing factor to the higher post-menopausal vulnerability to neurological disorders. Elucidating the relationship between insulin resistance associated with aging… CONTINUE READING

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