Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1

@article{Marsicano2002NeuroprotectivePO,
  title={Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1},
  author={G. Marsicano and B. Moosmann and H. Hermann and B. Lutz and C. Behl},
  journal={Journal of Neurochemistry},
  year={2002},
  volume={80}
}
Neuroprotective effects have been described for many can‐nabinoids in several neurotoxicity models. However, the exact mechanisms have not been clearly understood yet. In the present study, antioxidant neuroprotective effects of cannabinoids and the involvement of the cannabinoid receptor 1 (CB1) were analysed in detail employing cell‐free biochemical assays and cultured cells. As it was reported for oestrogens that the phenolic group is a lead structure for antioxidant neuroprotective effects… Expand
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