Neuroprotective effects on somatotopic maps resulting from piracetam treatment and environmental enrichment after focal cortical injury.

@article{Xerri2003NeuroprotectiveEO,
  title={Neuroprotective effects on somatotopic maps resulting from piracetam treatment and environmental enrichment after focal cortical injury.},
  author={Christian Xerri and Y Zennou-Azougui and J-O Coq},
  journal={ILAR journal},
  year={2003},
  volume={44 2},
  pages={110-24}
}
Acute and chronic postlesion reorganization of the cortical maps was examined in adult rats using electrophysiological mapping of the forepaw area in the primary somatosensory cortex. Recordings were made before and after (first 12 hr and 3 wk) induction of a focal thermal-ischemic lesion to a restricted part of the forepaw area. The influence of an anti-ischemic substance (piracetam) and housing in an enriched environment (EE) or impoverished environment (IE) on the organization of the spared… CONTINUE READING