Neuroprotective effects of xiao-xu-ming decoction against ischemic neuronal injury in vivo and in vitro.

@article{Zhu2010NeuroprotectiveEO,
  title={Neuroprotective effects of xiao-xu-ming decoction against ischemic neuronal injury in vivo and in vitro.},
  author={Xin-Hong Zhu and Shu-ji Li and Hong-hai Hu and Li-rong Sun and Manas Das and Tian-Ming Gao},
  journal={Journal of ethnopharmacology},
  year={2010},
  volume={127 1},
  pages={38-46}
}
ETHNOPHARMACOLOGICAL RELEVANCE Xiao-Xu-Ming decoction (XXMD) has long been employed clinically to treat stroke in traditional Chinese Medicine. AIM OF THE STUDY To investigate the neuroprotective effects of XXMD in vivo and in vitro stroke models and determine involved mechanisms. MATERIALS AND METHODS Two models (four-vessel occlusion in adult Wistar rats and oxygen-glucose deprivation primary cultured neurons) were employed to mimic ischemia-reperfusion damage, in vivo and in vitro… CONTINUE READING
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