Neuroprotective effects of soy phytoestrogens in the rat brain.

  title={Neuroprotective effects of soy phytoestrogens in the rat brain.},
  author={I{\~n}igo Azcoitia and Ana 6 Moreno and Paloma Carrero and Santiago Palacios and Luis Miguel Garcia-Segura},
  journal={Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology},
  volume={22 2},
Soy extracts are widely used as an alternative to hormone replacement therapy for the treatment of menopausal symptoms. Soy phytoestrogens, such as genistein, may act on the nervous system, affecting mood, cognitive function and behavior. In addition, several studies suggest that soy phytoestrogens are neuroprotective. The hypothesis of the present study was that soy extracts may exert neuroprotection and that this effect is mediated by phytoestrogens such as genistein. To test this hypothesis… CONTINUE READING


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