Neuroprotective effects of scutellarin against hypoxic-ischemic-induced cerebral injury via augmentation of antioxidant defense capacity.

@article{Guo2011NeuroprotectiveEO,
  title={Neuroprotective effects of scutellarin against hypoxic-ischemic-induced cerebral injury via augmentation of antioxidant defense capacity.},
  author={Hong Guo and Li-min Hu and Shao-xia Wang and Yu-Lin Wang and Fang Shi and Hui Li and Yang Liu and Li-yuan Kang and Xiumei Gao},
  journal={The Chinese journal of physiology},
  year={2011},
  volume={54 6},
  pages={399-405}
}
An increasing number of studies has indicated that hypoxic-ischemic-induced cerebral injury is partly mediated via oxidative stress. Recent researches have focused on searching for drug and herbal manipulations to protect against hypoxic-ischemic-induced oxidative cell damage. Scutellarin is a flavonoid derived from the Erigeron breviscapus (vant.) and has been reported to exhibit neuroprotective properties. However, its precise mechanism, particularly its antioxidation mechanism, remains… CONTINUE READING