Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells.

@article{Zhang2010NeuroprotectiveEO,
  title={Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells.},
  author={Li Zhang and Huixin Yu and Xincan Zhao and Xiufeng Lin and Chen Tan and Guoxian Cao and Zhengwu Wang},
  journal={Neurochemistry international},
  year={2010},
  volume={57 5},
  pages={547-55}
}
Beta-amyloid (Abeta) peptide, the hallmark of Alzheimer's disease (AD), invokes a cascade of oxidative damages to neurons and eventually leads to neuronal death. In this study, salidroside (Sald), an active compound isolated from a traditional Chinese medicinal plant, Rhodiola rosea L., was investigated to assess its protective effects and the underlying mechanisms against Abeta-induced oxidative stress in SH-SY5Y human neuroblastoma cells. Abeta(25-35)-induced neuronal toxicity was… CONTINUE READING
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