Neuroprotective effects of iron chelator Desferal on dopaminergic neurons in the substantia nigra of rats with iron-overload.

@article{Jiang2006NeuroprotectiveEO,
  title={Neuroprotective effects of iron chelator Desferal on dopaminergic neurons in the substantia nigra of rats with iron-overload.},
  author={Hong Jiang and Zhuo Luan and Jun Wang and Jun-xia Xie},
  journal={Neurochemistry international},
  year={2006},
  volume={49 6},
  pages={605-9}
}
The aim of the present study was to investigate whether the iron chelator Desferal prevents the degeneration of dopaminergic neurons in the substantia nigra (SN) induced by iron-overload in rats. Using fast cyclic voltammetry, tyrosine hydroxylase (TH) immunohistochemistry, Perls' iron staining, and high-performance liquid chromatography-electrochemical… CONTINUE READING