Neuroprotective effects of human mesenchymal stem cells on dopaminergic neurons through anti-inflammatory action.

@article{Kim2009NeuroprotectiveEO,
  title={Neuroprotective effects of human mesenchymal stem cells on dopaminergic neurons through anti-inflammatory action.},
  author={Y Kim and H S Park and Gwang Myeong Lee and Oh Young Bang and Young Hwan Ahn and Eunhye Joe and Hyun Ok Kim and Phil Hyu Lee},
  journal={Glia},
  year={2009},
  volume={57 1},
  pages={13-23}
}
Parkinson's disease (PD) is a common, progressive neurodegenerative disorder caused by the loss of dopaminergic neurons in the substantia nigra (SN). Numerous studies have provided evidence suggesting that neuroinflammation plays an important role in the pathogenesis of PD. In this study, we used lipopolysaccharide (LPS)-induced in vitro and in vivo inflammation models to investigate whether human mesenchymal stem cells (hMSCs) have a protective effect on the dopaminergic system through anti… CONTINUE READING