Neuroprotective effects of arachidonic acid against oxidative stress on rat hippocampal slices.

@article{Wang2006NeuroprotectiveEO,
  title={Neuroprotective effects of arachidonic acid against oxidative stress on rat hippocampal slices.},
  author={Ze-jian Wang and Cui-ling Liang and Guang-mei Li and Cai-yi Yu and Ming Yin},
  journal={Chemico-biological interactions},
  year={2006},
  volume={163 3},
  pages={207-17}
}
Arachidonic acid (AA), 5,8,11,14-eicosateraenoic acid is abundant, active and necessary in the human body. In the present study, we reported the neuroprotective effects and mechanism of arachidonic acid on hippocampal slices insulted by glutamate, NaN(3) or H(2)O(2)in vitro. Different types of models of brain injury in vitro were developed by 1mM glutamate, 10mM NaN(3) or 2mM H(2)O(2). After 30 min of preincubation with arachidonic acid or linoleic acid, hippocampal slices were subjected to… CONTINUE READING

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