Neuroprotective effects of N-stearoyltyrosine on transient global cerebral ischemia in gerbils.

@article{Zhang2009NeuroprotectiveEO,
  title={Neuroprotective effects of N-stearoyltyrosine on transient global cerebral ischemia in gerbils.},
  author={Yan-Bin Zhang and Meng-Yuan Kan and Zhi-hui Yang and Wen-long Ding and Jing He Zhangfei Li Yu Yi and HongZhuan Chen and Yang Lu},
  journal={Brain research},
  year={2009},
  volume={1287},
  pages={146-56}
}
N-stearoyltyrosine (NsTyr), a synthesized anandamide (AEA) analogue, was evaluated for the first time in the present study for the neuroprotective effect in gerbils subjected to transient global cerebral ischemia reperfusion (IR). The extent of ischemia injury was assessed behaviorally by measuring neurological functions, passive avoidance test and Morris water maze; and histopathologically by evaluating hippocampal CA1 pyramidal damage. In addition, ischemia-induced apoptosis was examined… CONTINUE READING