Neuroprotective effects of Magnoliae Flos extract in mouse hippocampal neuronal cells

  title={Neuroprotective effects of Magnoliae Flos extract in mouse hippocampal neuronal cells},
  author={Youn Sik Jung and Jin Bae Weon and Woo Seung Yang and Gahee Ryu and Choong Je Ma},
  journal={Scientific Reports},
Magnoliae Flos (MF) is a traditional medicinal herb used for managing rhinitis, sinusitis and headache. The purpose of the present study was to determine the neuroprotective effect of MF against glutamate-induced oxidative stress and to assess the underlying mechanism. Glutamate is a major endogenous excitatory neurotransmitter in the brain and contributes to the development of neurodegenerative diseases by excessive activation. MF extract was subjected to a neuroprotective effect assay in HT22… Expand
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Oxidative Stress Induces a Form of Programmed Cell Death with Characteristics of Both Apoptosis and Necrosis in Neuronal Cells
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Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
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  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1995
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Inhibitions of mast cell-derived histamine release by different Flos Magnoliae species in rat peritoneal mast cells.
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Effect of the essential oil from the flowers of Magnolia sieboldii on the lipopolysaccharide-induced production of nitric oxide and prostaglandin E2 by rat peritoneal macrophages.
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