Neuroprotective effect of subretinal implants in the RCS rat.

  title={Neuroprotective effect of subretinal implants in the RCS rat.},
  author={Machelle T. Pardue and Michael J Phillips and Hang Yin and Brian D Sippy and Sarah Webb-Wood and Alan Y. Chow and Sherry L. Ball},
  journal={Investigative ophthalmology & visual science},
  volume={46 2},
PURPOSE Retinal prosthetics have been designed to interface with the neural retina by electrically stimulating the remaining retinal circuits after photoreceptor degeneration. However, the electrical stimulation provided by the subretinal implant may also stimulate neurotrophic factors that provide neuroprotection to the retina. This study was undertaken to determine whether electrical stimulation from a subretinal photodiode-based implant has a neuroprotective effect on photoreceptors in the… CONTINUE READING
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