Neuroprotective effect of garlic compounds in amyloid-beta peptide-induced apoptosis in vitro.

@article{Peng2002NeuroprotectiveEO,
  title={Neuroprotective effect of garlic compounds in amyloid-beta peptide-induced apoptosis in vitro.},
  author={Qiaoling Peng and Amber R Buz'Zard and Benjamin H. S. Lau},
  journal={Medical science monitor : international medical journal of experimental and clinical research},
  year={2002},
  volume={8 8},
  pages={
          BR328-37
        }
}
BACKGROUND Neuronal apoptosis is one of the pathological features of Alzheimer's disease (AD) and is associated with senile plaques containing amyloid-b peptide (Abeta). Reactive oxygen species (ROS) are proposed to be involved in the apoptotic mechanism of Abeta-mediated neurotoxicity. The purpose of this study was to determine the effects of aged garlic extract (AGE) and S-allyl cysteine (SAC) on Abeta(25-35)-induced apoptosis and ROS generation in a rat pheochromocytoma (PC12) cell line… CONTINUE READING
Highly Cited
This paper has 46 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

The Drug Developments of Hydrogen Sulfide on Cardiovascular Disease

Oxidative medicine and cellular longevity • 2018
View 1 Excerpt