Neuroprotective effect of gacyclidine. A multicenter double-blind pilot trial in patients with acute traumatic brain injury.

@article{Lepeintre2004NeuroprotectiveEO,
  title={Neuroprotective effect of gacyclidine. A multicenter double-blind pilot trial in patients with acute traumatic brain injury.},
  author={J F Lepeintre and Pierre d'Arbigny and J-F Math{\'e} and Bernard Vigu{\'e} and Georges Loubert and J Delcour and Christian Kempf and Marc Tadi{\'e}},
  journal={Neuro-Chirurgie},
  year={2004},
  volume={50 2-3 Pt 1},
  pages={83-95}
}
The aim of this study was to assess the safety and efficacy of intravenous (IV) injections of gacyclidine, a novel NMDA receptor antagonist, for neurological and functional recovery following acute traumatic brain injury. This multicenter, prospective, randomized, placebo-controlled, double-blind study compared four parallel groups. Two IV doses were… CONTINUE READING