Neuroprotective effect of developmental docosahexaenoic acid supplement against excitotoxic brain damage in infant rats

@article{Hgyes2003NeuroprotectiveEO,
  title={Neuroprotective effect of developmental docosahexaenoic acid supplement against excitotoxic brain damage in infant rats},
  author={E Hgyes and Csaba Nyakas and Amanda J. Kiliaan and Tam{\'a}s Farkas and Botond Penke and Paul G. M. Luiten},
  journal={Neuroscience},
  year={2003},
  volume={119},
  pages={999-1012}
}
Long-chain polyunsaturated fatty acid (LC-PUFA) composition of neural membranes is a key factor for brain development, in chemical communication of neurons and probably also their survival in response to injury. Viability of cholinergic neurons was tested during brain development following dietary supplementation of fish oil LC-PUFAs (docosahexaenoic acid [DHA], eicosapentaenoic acid, arachidonic acid) in the food of mother rats. Excitotoxic injury was introduced by N-methyl-D,L-aspartate (NMDA… 
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