Neuroprotective effect of curcumin against oxidative damage in BV-2 microglia and high intraocular pressure animal model.

PURPOSE The involvement of local and systemic oxidative stress in intraocular pressure (IOP) elevation and optic nerve damage has been hypothesized in the pathogenesis of glaucoma. In this study, we aim to evaluate the antioxidant effects of curcumin in BV-2 microglia oxidative damage and assess its neuroprotective effects in a chronic high IOP rat model… (More)