Neuroprotective effect of brain-derived neurotrophic factor mediated by autophagy through the PI3K/Akt/mTOR pathway.

Abstract

Brain‑derived neurotrophic factor (BDNF) has been demonstrated to be a potent growth factor that is beneficial in neuronal functions following hypoxia‑ischemia (HI). Mature BDNF triggers three enzymes, mitogen‑activated protein kinase (MAPK), phosphatidylinositol 3‑kinase (PI3K) and phosphoinositide phospholipase C-γ (PLCγ), which are its predominant… (More)
DOI: 10.3892/mmr.2013.1628

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@article{Chen2013NeuroprotectiveEO, title={Neuroprotective effect of brain-derived neurotrophic factor mediated by autophagy through the PI3K/Akt/mTOR pathway.}, author={Ai Chen and Li-Jing Xiong and Yu Tong and Meng Mao}, journal={Molecular medicine reports}, year={2013}, volume={8 4}, pages={1011-6} }