Neuroprotective effect of berberine against learning and memory deficits in diffuse axonal injury.

@article{Wang2018NeuroprotectiveEO,
  title={Neuroprotective effect of berberine against learning and memory deficits in diffuse axonal injury.},
  author={Hong-Cai Wang and Bo-Ding Wang and Mao-Song Chen and Hai Chen and Cheng-Feng Sun and G. L. Shen and Jianmin Zhang},
  journal={Experimental and therapeutic medicine},
  year={2018},
  volume={15 1},
  pages={1129-1135}
}
The aim of the present study was to assess the neuroprotective effect of berberine against learning and memory deficits in diffuse axonal injury (DAI). DAI rats were orally gavaged with berberine at a dose of 200 mg/kg of body weight for 4 weeks. Behavioral tests were used to analyze the neuroprotective effect of berberine against DAI-induced learning and memory deficits. In the present study, treatment with berberine significantly protected against DAI-induced inhibition of learning and memory… CONTINUE READING
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