Neuroprotective effect of baicalin on compression spinal cord injury in rats

@article{Cao2010NeuroprotectiveEO,
  title={Neuroprotective effect of baicalin on compression spinal cord injury in rats},
  author={Yang Cao and Gang Li and Yan-feng Wang and Zhong-Kai Fan and Yun-long Bi},
  journal={Brain Research},
  year={2010},
  volume={1357},
  pages={115-123}
}
The current study was performed to investigate the effect of baicalin (BC) on spinal cord injury (SCI) in rat. BC (10, 30 and 100mg/kg, i.p., respectively) was administered to rats immediately and every 24h following SCI. The BC therapy (100mg/kg) dramatically decreased (1) the water content of spinal cord tissue (by dry-wet weight method), (2) the permeability of blood-spinal cord barrier (measured by Evans blue), (3) oxidant stress (malondialdehyde values and glutathione levels evaluation… CONTINUE READING

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