Neuroprotective effect of afobazole on rats with bilateral local photothrombosis of vessels in the prefrontal cortex

Abstract

We studied the neuroprotective effect of a new selective anxiolytic afobazole on rats with bilateral focal ischemic stroke in the prefrontal cortex caused by photothrombosis. Intraperitoneal injection of 5 mg/kg afobazole 1 h after surgery and over the next 8 days (daily treatment) produced a neuroprotective effect. Afobazole was far superior to the… (More)
DOI: 10.1007/s10517-008-0051-4

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