Neuroprotective compounds from Reynoutria sachalinensis

  title={Neuroprotective compounds from Reynoutria sachalinensis},
  author={Min Rye Eom and Jin Bae Weon and Youn Sik Jung and Gahee Ryu and Woo Seung Yang and Choong Je Ma},
  journal={Archives of Pharmacal Research},
Glutamate is a neurotransmitter in central nervous system. Overexpression of glutamate leads to oxidative stress, resulting in several neurodegenerative disorders that include Alzheimer’s disease. The n-hexane fraction of stems and ethyl acetate (EtOAc) fraction of flowers of Reynoutria sachalinensis provide neuroprotection against glutamate-induced oxidative toxicity in HT22 cells. In this study, 1-decanol (1), β-amyrin (2), dammaran-3β-ol (3), campesterol (4), daucosterol (5), ergosterol… Expand
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