Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271.

Abstract

BAY 38-7271 is a new high-affinity cannabinoid receptor agonist with strong neuroprotective efficacy in a rat model of traumatic brain injury (acute subdural hematoma, SDH). In the present study we investigated CB1 receptor signal transduction by [35S]GTPgammaS binding in situ and in vitro to assess changes in receptor functionality after SDH. Further, we… (More)

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Cite this paper

@article{Mauler2003NeuroprotectiveAB, title={Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271.}, author={Frank Mauler and Volker C. Hinz and Karl Heinz Augstein and Marion Fassbender and Ervin Horv{\'a}th}, journal={Brain research}, year={2003}, volume={989 1}, pages={99-111} }