Neuroprotective activity of omega-3 fatty acids against epilepsy-induced hippocampal damage: Quantification with immunohistochemical for calcium-binding proteins.

@article{Ferrari2008NeuroprotectiveAO,
  title={Neuroprotective activity of omega-3 fatty acids against epilepsy-induced hippocampal damage: Quantification with immunohistochemical for calcium-binding proteins.},
  author={Danuza Ferrari and Roberta Monterazzo Cysneiros and Carla Alessandra Scorza and Ricardo Mario Arida and Esper Abr{\~a}o Cavalheiro and A-C G de Almeida and Fulvio Alexandre Scorza},
  journal={Epilepsy & behavior : E&B},
  year={2008},
  volume={13 1},
  pages={36-42}
}
To investigate whether n-3 polyunsaturated fatty acids (n-3 PUFAs) would promote different morphological changes in the hippocampal formation of rats with epilepsy, we performed an immunocytochemical study using parvalbumin (PV) and calretinin (CR) distribution as a marker. Animals subjected to the experimental model of epilepsy with a single dose of pilocarpine were randomly divided into the following groups: animals with epilepsy treated daily with vehicle (EV) and animals with epilepsy… CONTINUE READING