Neuroprotective Potential of Peroxisome Proliferator Activated Receptor-α Agonist in Cognitive Impairment in Parkinson's Disease: Behavioral, Biochemical, and PBPK Profile

@inproceedings{Uppalapati2014NeuroprotectivePO,
  title={Neuroprotective Potential of Peroxisome Proliferator Activated Receptor-α Agonist in Cognitive Impairment in Parkinson's Disease: Behavioral, Biochemical, and PBPK Profile},
  author={Dedeepya Uppalapati and Nihar Ranjan Das and Rahul Prakashchand Gangwal and Mangesh V. Damre and Abhay T. Sangamwar and Shyam Sunder Sharma},
  booktitle={PPAR research},
  year={2014}
}
Parkinson's disease (PD) is a common neurodegenerative disorder affecting 1% of the population by the age of 65 years and 4-5% of the population by the age of 85 years. PD affects functional capabilities of the patient by producing motor symptoms and nonmotor symptoms. Apart from this, it is also associated with a higher risk of cognitive impairment that may lead to memory loss, confusion, and decreased attention span. In this study, we have investigated the effect of fenofibrate, a PPAR… CONTINUE READING
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