Neuroprotective Mechanisms of Natural Polyphenolic Compounds

  title={Neuroprotective Mechanisms of Natural Polyphenolic Compounds},
  author={M{\'a}ria Kov{\'a}csov{\'a} and Andrej Barta and Jana Parohov{\'a} and Stanislava Vrankov{\'a} and Olga Pechanova},
Natural polyphenols have been reported to exert beneficial effects in preventing cardiovascular diseases but their neuroprotective mechanisms were studied much less. The review is focused on biochemical pathways and molecular neuroprotective mechanisms of natural polyphenols in the brain particularly; of course in close relation to neurophysiological and pathophysiological consequences. This review provides the evidence that antioxidant activity, mainly inhibition of the NADPH oxidase and… CONTINUE READING


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