Neuroprotective Effects of Metallothionein Against Rotenone-Induced Myenteric Neurodegeneration in Parkinsonian Mice

@article{Murakami2014NeuroprotectiveEO,
  title={Neuroprotective Effects of Metallothionein Against Rotenone-Induced Myenteric Neurodegeneration in Parkinsonian Mice},
  author={Shinki Murakami and Ikuko Miyazaki and Norio Sogawa and Ko Miyoshi and Masato Asanuma},
  journal={Neurotoxicity Research},
  year={2014},
  volume={26},
  pages={285-298}
}
Parkinson’s disease (PD) is a neurodegenerative disease with motor symptoms as well as non-motor symptoms that precede the onset of motor symptoms. Mitochondrial complex I inhibitor, rotenone, has been widely used to reproduce PD pathology in the central nervous system (CNS) and enteric nervous system (ENS). We reported previously that metallothioneins (MTs… CONTINUE READING