Neuroprotective Effects and Mechanisms of Curcumin–Cu(II) and –Zn(II) Complexes Systems and Their Pharmacological Implications

@inproceedings{Yan2017NeuroprotectiveEA,
  title={Neuroprotective Effects and Mechanisms of Curcumin–Cu(II) and –Zn(II) Complexes Systems and Their Pharmacological Implications},
  author={Fa-Shun Yan and Jian-Long Sun and Wen-Hai Xie and Liang Shen and Hong-Fang Ji},
  booktitle={Nutrients},
  year={2017}
}
Alzheimer's disease (AD) is the main form of dementia and has a steadily increasing prevalence. As both oxidative stress and metal homeostasis are involved in the pathogenesis of AD, it would be interesting to develop a dual function agent, targeting the two factors. Curcumin, a natural compound isolated from the rhizome of Curcuma longa, is an antioxidant… CONTINUE READING