Neuroprotective Antioxidants from Marijuana a

@article{Hampson2000NeuroprotectiveAF,
  title={Neuroprotective Antioxidants from Marijuana a},
  author={Aidan J. Hampson and Maurizio Grimaldi and Marica Loli{\'c} and David A Wink and R. Rosenthal and Julius Axelrod},
  journal={Annals of the New York Academy of Sciences},
  year={2000},
  volume={899}
}
Abstract: Cannabidiol and other cannabinoids were examined as neuroprotectants in rat cortical neuron cultures exposed to toxic levels of the neurotransmitter, glutamate. The psychotropic cannabinoid receptor agonist Δ9‐tetrahydrocannabinol (THC) and cannabidiol, (a non‐psychoactive constituent of marijuana), both reduced NMDA, AMPA and kainate receptor mediated neurotoxicities. Neuroprotection was not affected by cannabinoid receptor antagonist, indicating a (cannabinoid) receptor‐independent… Expand
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