Neuroprotection by estrogen in the brain: the mitochondrial compartment as presumed therapeutic target.

@article{Arnold2009NeuroprotectionBE,
  title={Neuroprotection by estrogen in the brain: the mitochondrial compartment as presumed therapeutic target.},
  author={Susanne Arnold and Cordian Beyer},
  journal={Journal of neurochemistry},
  year={2009},
  volume={110 1},
  pages={1-11}
}
Neuroprotection by estrogen in the CNS is well-documented and comprises the intricate regulation of cell-cell communication between neurons and supportive non-neuronal glial cells. It is assumed that these interactions are essential for cell survival under pathological and toxic conditions by regulating the allocation of trophic molecules, e.g., growth factors, controlling relevant intracellular anti-apoptotic and death cascades, and attenuating inflammatory processes. Malfunction and… CONTINUE READING

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