Neuroprotection by Vitamin C Against Ethanol-Induced Neuroinflammation Associated Neurodegeneration in the Developing Rat Brain.

@article{Ahmad2016NeuroprotectionBV,
  title={Neuroprotection by Vitamin C Against Ethanol-Induced Neuroinflammation Associated Neurodegeneration in the Developing Rat Brain.},
  author={Ashfaq Ahmad and Shahid ali Shah and Haroon Badshah and Min Ju Kim and Tahir Ali and Gwang Ho Yoon and Tae Hyun Kim and Nouman B Abid and Shafiq Ur Rehman and Sohail Rafi Khan and Myeong Ok Kim},
  journal={CNS & neurological disorders drug targets},
  year={2016},
  volume={15 3},
  pages={360-70}
}
Ethanol induces oxidative stress and its exposure during early developmental age causes neuronal cell death which leads to several neurological disorders. We previously reported that vitamin C can protect against ethanol-induced apoptotic cell death in the developing rat brain. Here, we extended our study to understand the therapeutic efficacy of vitamin C against ethanol-induced oxidative stress, neuroinflammation mediated neurodegeneration in postnatal day 7 (PND7) rat. A single episode of… CONTINUE READING
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