Neuroprotection by Brazilian Green Propolis against In vitro and In vivo Ischemic Neuronal Damage

@article{Shimazawa2005NeuroprotectionBB,
  title={Neuroprotection by Brazilian Green Propolis against In vitro and In vivo Ischemic Neuronal Damage},
  author={Masamitsu Shimazawa and Satomi Chikamatsu and Nobutaka Morimoto and Satoshi Mishima and Hiroichi Nagai and Hideaki Hara},
  journal={Evidence-based Complementary and Alternative Medicine},
  year={2005},
  volume={2},
  pages={201 - 207}
}
  • Masamitsu Shimazawa, Satomi Chikamatsu, +3 authors Hideaki Hara
  • Published 2005
  • Medicine
  • Evidence-based Complementary and Alternative Medicine
  • We examined whether Brazilian green propolis, a widely used folk medicine, has a neuroprotective function in vitro and/or in vivo. In vitro, propolis significantly inhibited neurotoxicity induced in neuronally differentiated PC12 cell cultures by either 24 h hydrogen peroxide (H2O2) exposure or 48 h serum deprivation. Regarding the possible underlying mechanism, propolis protected against oxidative stress (lipid peroxidation) in mouse forebrain homogenates and scavenged free radicals [induced… CONTINUE READING

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