Neuroplasticity in children

  title={Neuroplasticity in children},
  author={Nandini Mundkur},
  journal={The Indian Journal of Pediatrics},
  • N. Mundkur
  • Published 1 October 2005
  • Medicine
  • The Indian Journal of Pediatrics
Research in the field of neurosciences and genetics has given us great insight into the understanding of learning and behavior and changes in the brain in resonse to experience. It is seen that brain is dynamically changing throughout life and is capable of tearing at any time. Critical periods of neuroplasticity for various streams of development are also beter understood. Technological advances in non invasive imaging techniques and advances in moleculoar genetics have helped us understand… 

Neuroplasticity, psychosocial genomics, and the biopsychosocial paradigm in the 21st century.

Findings from these new sciences provide external validation for the biopsychosocial perspective and offer important insights into the manifold means by which socioenvironmental experiences influence neurobiological structure and function across the life course.

Cortical Visual Impairment in Childhood: ‘Blindsight’ and the Sprague Effect Revisited

Support is provided for diverse processes of brain plasticity in visual function after damage in infancy and childhood in comparison with injury that occurs in the adult brain and within the context of “blindsight” and the “Sprague Effect”.

Neuroplasticity in Early Onset Multiple Sclerosis.

Researchers should respect the importance of neuroplasticity in early onset multiple sclerosis, as the facilitation of this phenomenon can provide an injured brain with a better opportunity to recover.

Can exercise make our children smarter?

Purpose. The aim of this study is to reveal the effects of exercise on the brain structure and function in children, and to analyze methodological approach applied in the researches of this topic.

Memory in Paediatric Temporal Lobe Epilepsy

These protocols add value to the diagnosis of memory impairments associated with paediatric TLE and provide a better understanding of pre-operative memory profile at the individual level, and contribute towards the use of memory fMRI in the surgical decision-making process.

Effect of Neuroplasticity-based BrainFit® Mind Exercises on Attention Skills of Primary School Students

The purpose of this study is to investigate the effect of BrainFit® mind exercises based on neuroplasticity on the affective characteristics of primary school students, such as impulsivity, auditory

Neurotoxins and Neurodevelopment

The context of neurotoxins and the mechanisms by which in utero and postnatal exposure can affect neural development and function are introduced and other moderating factors are identified.


A critical review on the effect of currently available treatment modalities of Ayurveda that can efficiently manage Cerebral palsy is provided.

Impact of perinatal hypoxia on the developing brain.

A broader spectrum of recent results from studies on mechanisms leading to hypoxia-induced injury is covered, and the impact of these pathophysiological changes on the structure and development of the brain, especially on its regions: corpus striatum and hippocampus is studied.

Stem Cell Therapy for Cerebral Palsy – A Novel Option

The discovery of stem cells by James Till and Ernest McCulloch in 1961 provided a foundation for further breakthroughs in the field ofstem cells, and Sir Martin J. Evans along with Mario R. Capecchi, and Oliver Smithies were jointly awarded a Nobel Prize for their contribution in introducing specific gene modifications in mice by the use of embryonic stem cells.



Sculpting the developing brain.

This exploratory tool and other new clinical methods demonstrate how the brain's functional "maps" undergo major reorganization in response to early environmental changes.

Review : Metabolic Imaging: A Window on Brain Development and Plasticity

Measurement of the absolute rates of glucose utilization with PET reveals that during the major portion of the first decade, the human brain has a higher energy (glucose) demand compared with both the newborn and adult brains.

Clinical disorders of brain plasticity

  • M. Johnston
  • Psychology, Medicine
    Brain and Development
  • 2004

Learning, Memory, and Transcription Factors

Evidence that disruptions in these pathways are involved in human cognitive disorders, including neurofibromatosis type I, Coffin-Lowry syndrome, Rubinstein-Taybi syndrome, Rett syndrome, tuberous sclerosis-2, Down syndrome, X-linked α-thalassemia/mental retardation, cretinism, Huntington disease, and lead poisoning are summarized.

Language recovery after left hemispherectomy in children with late‐onset seizures

Recovery of higher level receptive and, to a lesser extent, expressive language functions is attributed to plasticity of the right hemisphere, which appears to persist beyond the proposed critical period for language acquisition and lateralization.

The neurotrophin hypothesis for synaptic plasticity

Cortical plasticity: from synapses to maps.

The goal of the current paper is to review the fields of both synaptic and cortical map plasticity with an emphasis on the work that attempts to unite both fields, to highlight the gaps in the understanding of synaptic and cellular mechanisms underlying cortical representational plasticity.

Cognitive impairment in Coffin–Lowry syndrome correlates with reduced RSK2 activation

A correlation between human cognitive performance and cellular capacity to activate RSK2 is suggested and provides additional evidence that the CREB kinase, R SK2, and CREB phosphorylation may play important roles in human learning and memory, as they do in lower animals.

Long-term potentiation--a decade of progress?

A simple model is described that unifies much of the data that previously were viewed as contradictory about the molecular mechanisms of this long-lasting increase in synaptic strength in the hippocampus.