Neuroplasticity in addiction: cellular and transcriptional perspectives

  title={Neuroplasticity in addiction: cellular and transcriptional perspectives},
  author={Heather Bronwyn Madsen and Robyn Mary Brown and Andrew J Lawrence},
  booktitle={Front. Mol. Neurosci.},
Drug addiction is a chronic, relapsing brain disorder which consists of compulsive patterns of drug-seeking and taking that occurs at the expense of other activities. The transition from casual to compulsive drug use and the enduring propensity to relapse is thought to be underpinned by long-lasting neuroadaptations in specific brain circuitry, analogous to those that underlie long-term memory formation. Research spanning the last two decades has made great progress in identifying cellular and… CONTINUE READING
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